ABSTRACT
Objective:To explore the influences of Xingnao Tongdu acupuncture combined with Brunnstrom staging training on rehabilitation effect in stroke patients during recovery.Methods:According to random number table method, 82 patients with stroke during recovery who met inclusion criteria in Rehabilitation Medicine Department of the hospital were divided into control group (receiving routine rehabilitation training combined with Xingnao Tongdu acupuncture) and observation group (Brunnstrom staging training on basis of control group) between February 2020 and February 2021, 41 cases in each group. Both groups were continuously treated for 4 weeks. Before and after treatment, the severity of neurological deficits was evaluated by National Institute of Health Stroke Scale (NIHSS). The limb motor function was evaluated by Fugl-Meyer Assessment (FMA). The self-care ability was assessed by Barthel Index (BI). IL-6 was detected by ELISA. CRP level was detected by immunoturbidimetry. The WBC was detected by blood analyzer. The adverse reactions during treatment were observed. The clinical curative effect was evaluated.Results:There 40 cases in observation group and 41 cases in the control group were included into the statistics. The difference in total response rate between observation group and control group was not statistically significant [90.0% (36/40) vs. 75.6% (31/41)] ( χ2=2.93, P=0.087). After treatment, NIHSS score (6.65±1.79 vs. 8.71±2.61, t=4.13) in observation group was significantly lower than that of the control group ( P<0.01), while FMA score (69.56±9.64 vs. 61.77±10.33, t=3.51) and BI (73.72±8.34 vs. 65.86±7.36, t=4.50) were significantly higher than those in the control group ( P<0.01). The levels of serum IL-6 and CRP in observation group were significantly lower than those in the control group ( t values were 5.95, 5.61, respectively, all Ps<0.01). There were no adverse reactions in either group during treatment. Conclusion:The Xingnao Tongdu acupuncture combined with Brunnstrom staging training can improve rehabilitation effect and reduce levels of serum inflammatory cytokines in stroke patients during recovery.
ABSTRACT
Objective:To evaluate the clinical curative effect of Shenqi-Gushen Decoction on patients with chronic renal failure (CRF) of qi-yin deficiency syndrome. Methods:A total of 82 patients with CRF meeting inclusion criteria in the hospital were enrolled between June 2018 and January 2021. According to random number table method, they were divided into control group and observation group, 41 in each group. The control group was treated with routine western medicine, while the observation group was treated with Shenqi-Gushen Decoction on basis of control group. All were treated for 2 months. Before and after treatment, Traditional Chinese Medicine (TCM) symptoms were scored. The serum creatinine (SCr) and blood urea nitrogen (BUN) were detected by full-automatic biochemical analyzer. The levels of IL-6, TNF-α and hypersensitive C-reactive protein (hs-CRP) were detected by ELISA. The levels of hemoglobin (Hb), serum albumin (Alb) and prealbumin (PA) were detected by immune scatter turbidity. And clinical curative effect was evaluated. Results:The total response rate [80.5% (33/41) vs. 46.3% (19/41); χ2=5.861, P=0.015] in the observation group was significantly higher than that of the control group. After treatment, scores of TCM symptoms in observation group was significantly lower than that of the control group ( t=23.468, P<0.01), levels of serum SCr [(421.19 ± 43.82) μmol/L vs. (488.71 ± 48.39) μmol/L, t=6.623] and BUN [(19.54 ± 1.26) mmol/L vs. (24.12 ± 2.42) mmol/L, t=10.749] were significantly lower than those in the control group ( P<0.01), and eGFR [(47.71 ± 4.68) ml/min vs. (42.51 ± 4.55) ml/min, t=5.101] was significantly higher than that of control group ( P<0.01). After treatment, levels of serum IL-6, TNF-α and hs-CRP in observation group were significantly lower than those in the control group ( t=3.412, 3.714, 2.466, P<0.01 or P<0.05), while levels of Hb, Alb and PA were significantly higher than those in the control group ( t=4.462, 5.807, 2.256, P<0.01 or P<0.05). Conclusion:Shenqi-Gushen Decoction combined with routine western medicine can improve clinical syndromes, renal function, micro-inflammation response, nutrition status and curative effect in patients with CRF of qi-yin deficiency syndrome.